Van de Ven Brace Halts The Toffees' Unbeaten Streak at Brand New Stadium
The Dutch defender became the first defender to score twice in a English top-flight match for Spurs since the Belgian defender in spring 2013.
At a glance
The Spurs defender heads home twice in first half
The home side's Jake O'Brien has equalizer disallowed after VAR review
Senegalese midfielder scores final goal in 89th minute
The defeat is the Merseyside club's initial at Hill Dickinson Stadium
The Tottenham defender scored twice as Tottenham extended their unbeaten run on the road in the top division and handed Everton their first defeat at Hill Dickinson Stadium.
The Toffees were unbeaten in their last five matches at their recently opened stadium at the dockside location, having departed their historic home behind after 133 years at the end of the previous campaign.
But Tottenham's leader the Dutchman struck twice from corners in the opening 45 minutes to put their strong form at jeopardy, and they were failed to mount a comeback before the midfielder - set up by ex-Everton forward Richarlison - headed home a third to put the game to bed.
Jake O'Brien believed he had equalized the scores five minutes after the defender's opener, glancing a bullet header past Guglielmo Vicario from an set-piece.
The Portuguese striker, in the meantime, missed a handful of chances, while the Italian goalkeeper made a succession of excellent stops to ensure the London club went five away games without defeat in the English top flight.
But the video assistant referee stepped in, advising Craig Pawson to check the goal on the pitchside monitor and the referee ruled that the winger and Iliman Ndiaye were in offside positions and had interfered with the Tottenham goalkeeper.
The win moves Thomas Frank's side up to third in the division, a handful of points off local foes and table-toppers the Gunners.
Everton remain 14th and are six points ahead of the drop zone.
Tottenham analysis: Van de Ven fulfils duties at each end of the field
Following a drab weekday display in the Champions League against Monaco, where they managed a only attempts on goal, Frank opted for Randal Kolo Muani up front instead of former Toffees player the Brazilian.
The new arrival was unable to influence the game before being replaced for the substitute after an hour on the pitch, but it turns out he proved unnecessary in the final outcome.
Centre-back the Dutchman transformed into an attacking force to be reckoned with.
Tottenham's opening strike came from a cleverly executed set-piece play, with the midfielder heading the ball toward the face of goal for an free the defender to score.
And the captain - stepping up as skipper in Cristian Romero's unavailability - added his next goal in first-half stoppage time as he outjumped the England keeper to nod in.
The Dutchman was just as impressive in defensive duties, partnering well with Kevin Danso as the duo dealt superbly with the 34 crosses sent their way by Everton.
Toffees breakdown: Everton lacking finishing touch
The club's recent stadium had been a fortress, but it appears the freshness may have worn off somewhat and supporters headed to the exits after Sarr's final goal for Tottenham.
The end in Everton's winning streak at home won't be a massive concern for the manager, but their striker situation are.
Beto and Thierno Barry - the Toffees' pair of recognised strikers - had netted only a single goal combined before the weekend's match.
And they were failed to add to that poor record on a wet and gloomy night on in Liverpool.
The striker's form was summed up when he chose to overhead kick a golden opportunity from near the goal, even with having room and time to reposition for a more conventional attempt that would have challenged the keeper.
The substitute, as well, failed to influence the game after replacing the starter in the 65th minute.
It was not for a shortage of chance. Most of Everton's attacks came through the winger and the forward, who relentlessly delivered dangerous balls into the Spurs box.
What next for both teams?
Everton: Moyes' men travel to Sunderland in the Premier League on early November at 20:00 GMT.
Spurs: The London club travel to St James' Park on Wednesday, 29 October for their fourth-round Carabao Cup match against Newcastle.